Health & Medical

World’s first anti-HIV gel enters trial phase – Daily Nation

World’s first anti-HIV gel enters trial phase – Daily Nation

In Summary UniPron has been found to not only act against HIV but can also be used to protect against pregnancy by killing sperms and as a lubricant.If the human trials are successful, Kenya could be the first country in the world to put an effective anti-HIV microbicide in the market.UniPron, explains Dr Mwethera, the…

In Summary

  • UniPron has been chanced on to no longer handiest act against HIV nevertheless can furthermore be damaged-all the manner down to provide protection to against pregnancy by killing sperms and as a lubricant.
  • If the human trials are worthwhile, Kenya would possibly maybe maybe well be the principle nation on this planet to effect an efficient anti-HIV microbicide available in the market.
  • UniPron, explains Dr Mwethera, the principle inventor, has lemon juice and various parts.
  • The an identical acidic ranges conclude no longer allow sperm to continue to exist, hence its capacity as a contraceptive.
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 AGGREY OMBOKI

By AGGREY OMBOKI


Extra by this Author

A gel developed in Kenya that can assassinate the Aids-causing virus is coming into a serious trial segment, with a minimal of Sh200 million spent on it prior to now 11 years.

Patented in 2007, UniPron has been chanced on to no longer handiest act against HIV nevertheless can furthermore be damaged-all the manner down to provide protection to against pregnancy by killing sperms and as a lubricant.

The drug developed at the Institute of Primate Learn (IPR), a Articulate company, is now predicament for the final human clinical trials, in step with essential investigator Peter Gichuhi Mwethera.

INNOVATION

“For the following and final segment, now we have effect together a solid crew of teachers, clinicians, merchants and marketers,” says Dr Mwethera, whose crew used to be early this 12 months awarded in London for the innovation.

Dr Kavoo Linge, a educated gynaecologist at Nairobi Nicely being facility and the clinical adviser to the project, acknowledged they are already looking out for ethical and statutory approvals for the proposed trials. “We’re in discussions with plenty of establishments with the requisite skill and details to entire human clinical trials of the very most attention-grabbing quality and ethical requirements,” he acknowledged

If the human trials are worthwhile, Kenya would possibly maybe maybe well be the principle nation on this planet to effect an efficient anti-HIV microbicide available in the market.

A microbicide, in step with the World Nicely being Organisation, is a substance applied contained in the vagina or rectum to reduce the transmission of sexually transmitted infections, including HIV.

Even though for the time being such a suitable microbicide does no longer exist, one map it would work is by affirming an acidic environment to provide protection to against infection.

UniPron, explains Dr Mwethera, the principle inventor, has lemon juice and various parts.

ACIDIC

“It if truth be told works by reducing and stabilising the environment at ranges that are too acidic for HIV to continue to exist,” he says.

The an identical acidic ranges conclude no longer allow sperm to continue to exist, hence its capacity as a contraceptive.

Dr Mwethera outlined that they’ve published 25 papers in inquire reviewed scientific journals on UniPron, as wisely as generated one PhD and two Masters college students.

UniPron, a winner of the 2019 Kenya National Innovation Company/Newton Fund Award, used to be in February amongst enhancements from all the map by the sector showcased at the entrepreneurial mentorship programme organised by the Royal Academy of Engineering in London.

In 2015, UniPron received the Tony Elumelu Entrepreneurship Award and Africa Union Innovation Award in 2013.

“That is a product with global capacity,” acknowledged Mr Stuart Nicol, an investment adviser who is consulting on UniPron for the UK’s Royal Academy of Engineering.

UNIPRON

Mr Nicol used to be in Nairobi no longer too long prior to now to talk in regards to the capacity of manufacturing UniPron in the UK for the American and European markets.

“Whereas UniPron has colossal capacity, in the meanwhile it will furthermore very wisely be some distance more straightforward to market two of its by-products that are already available in the market to merchants in Europe,” Mr Nicol instructed the Sunday Nation.

As a result of of the colossal sources and long sessions required to successfully assemble and commercialise this form of research product, Dr Hastings Ozwara, director IPR, acknowledged they’d to contemplate out of the sphere.

“Our biggest project, love, hundreds of various innovators in Kenya, used to be how to transfer the research from laboratory to the market — crossing what is is known as the valley of death,” acknowledged Dr Ozwara.

CLINICAL TRIALS

They then determined to assemble UniPron’s lubrication capacity separately because it didn’t require lengthy human clinical trials, not like for contraceptives or a HIV-killing drug.

In 2010, working with Standard Company, a native pharmaceutical producer, the scientists effect two products available in the market: Smugel lubricating gel and Smuscan ultrasound gel.

“However the closing prize is UniPron as an anti-HIV microbicide and contraceptive,” acknowledged Prof Isaac Macharia, a senior clinical manual and adviser to the project.



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